Thursday, August 8, 2019

Ayucafe – Live chat - Uses of Ajawain (Trachyspermum ammi) According to Ayurveda



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All views shared here are only for knowledge. This information doesn’t have any scientific validation. Various doctors and non-medicos have shared their views and experiences in this discussion. Please do not try any of the suggestions described here, without prior consult from your regular, qualified doctor. Dr. Prerak Shah and no other person is responsible for any unwanted effects, side effects or contra-indications in your health. Thank you.
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Ayucafe – Live chat Topic of Discussion: Uses of Ajawain (Trachyspermum ammi) According to Ayurveda
Ayulink Ayurveda: it is laghu, ruksha, tikshna, kapha-vata pacifying and pitta increasing
37811: Vat kaphnashak, Agnideepak , Pachak
Ayulink Ayurveda: vipaka katu and ushna virya
Prasad N Dhule: पेट के दर्द... मंदग्नी में use करते है
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Dr. Bhavin Chavda: Kapha shamak or khansi me useful
37811: Kruminashak
Dr. Jigar Joshi: Aamvat me useful
37811: Vedanashamak. In cold and headache hot ajwain fomentation gives superb relief
Dr. Bhavin Chavda: Ama hara Shola hara
Dr. Arvind Shahane: In udaradhman Ajwain + black salt Very useful home remedy
Ayulink Ayurveda: It is useful in almost all respiratory disorders
AFP: Ajmo + Jaggery - Urticaria
Dr. Archana Panchal: In urticaria ajwain haldi very useful
Ayulink Ayurveda: friends pl share recipe also - how to use in particular conditions for example, ajwain churna to eat in mandagni. ajwain for steam inhalation in cold. With cotton bag like pind sveda?
Dr. Arvind Shahane: Please specify hot Ajwain formation
37811: Yes
Ayulink Ayurveda: i use it - pind sveda (cotton bag) in aamavata condition
37811: Just roast 1tsp ajwain on iorn pot inhale smoke then keep it in small handkerchief and slowly smell it
Ayulink Ayurveda: Very good to use in kids
89967: In excess amount -- can it cause burning micturition and piles problem ???
Vd. Dhruti Kagrana: Ruchikara
37811: Yes. Shek- Dry swed
Ayulink Ayurveda: It is diuretic too. But in excess it can cause side effects with ushba virya
37811: After delivery used for dhupan with other ingredients for baby and mother
Ayulink Ayurveda: Very strong smell due to volatile oil in it
Dr. Nahida Tarannum: It is vata anulomak..gives best results in indigestion too..
AFP: Ajmo - Good in spasmodic pain
Ayulink Ayurveda: Sometimes smell / local application of volatile oil can cause skin irritations
37811: Yes so when we used in wheat flour paratha to make it easily digestive
Ayulink Ayurveda: It is described as krumighna in the books. Good - it increases Ruchi in the food
06050: Ajmo salt & hingu give relief in gastric pain
37811: Yes always first tried in stomach aches
Dr. Yashswi Mehta: What's ratio ajmo+ jaggery...?
Ayulink Ayurveda: It is also mentioned in the book as hruday uttejak
AFP: Ajmo 1part Jaggery 3part
37811: I used in mukhavas with variali ( badishep) and Til( sesame) kala namak
AFP: Ajmo is also given good result in PMS  & Kashtaartava
Dr. Arvind Shahane: As a daily mukhwas or like vatshamak mukhwas?
Ayulink Ayurveda: Is there any ready made formula with Ajwain as main ingredient ?
37811: Daily
AFP: Ajmodadi vati
Ayulink Ayurveda: Ajmidadi churna? Vati?
AFP: Ajmodadi vati  - Ref : Aryabhishaka
Ayulink Ayurveda: It is also good to control hikka
 I think it is used in dhoompan - Nirdosh herbal cig
88776: Ajvain : katu, tikt, laghu, ruksh, ushna, dipak, grahi, vatnashak, kafanashak, pittakarak. shul nashak , krimi nashak , hikka aamvata, aanah, aruchi nashak.
AFP: Frequent Urination : Ajmo  + Til(Sesame)
Ayucafe 032019 23: Ajwain with its characteristic aromatic smell and pungent taste is widely used as a spice in curries. Its seeds are used in small quantities for flavoring numerous foods, as preservatives, in medicine and for the manufacture of essential oil in perfumery. In Indian system of medicine, ajwain is administered for curing stomach disorders, a paste of crushed fruits is applied externally for relieving colic pains; and a hot and dry fomentation of the fruits is applied on chest for asthma. T. ammi has been shown to possess antimicrobial,  hypolipidemic, digestive stimulant, antihypertensive, hepatoprotective, antispasmodic, broncho-dilating,  antilithiasis, diuretic,  abortifacient ,  antiinflammatory, antitussive, antifilarial,  gestroprotective, nematicidal, anthelmintic, detoxification of aflatoxins and ameliorative effects.Therapeutic uses of T. ammi fruits include; stomachic, carminative and expectorant, antiseptic and amoebiasis, antimicrobial. Seeds soaked in lemon juice with Prunus amygdalus (badam) are given in curing amenhorroea and it is also used as antipyretic, febrifugal and in the treatment of typhoid fever.

Antihypertensive, antispasmodic and broncho-dilating activity
The antihypertensive effect of T. ammi administered intravenously in vivo, and the antispasmodic and broncho-dilating actions in vitro showed that calcium channel blockade has been found to mediate the spasmolytic effects of plant materials and it is being considered that this mechanism contributed to their observed result and supported the traditional use of T. ammi in hyperactive disease states of the gut such as colic and diarrhea as well as in hypertension.
Hepatoprotective activity The hepatoprotective actions in vivo showed that T. ammi was 80% protective in mice against a normally-lethal dose of paracetamol (1 g/kg), it prevented the CCl4-induced prolongation of pentobarbital sleeping time in mice, and it tended to normalize the high serum levels of liver enzymes caused by CCl4-induced liver damage in rats.
Antilithiasis and diuretic activity
Antilithiasis and diuretic actions in vivo of T. ammi on inhibiting oxalate urolithiasis induced in rats are also studied. In a further study of a possible diuretic effect, it was found that T. ammi was not effective in increasing the 24-h urine production. The results concluded that the traditional use of T. ammi in the treatment of kidney stones was not supported by their experimental evidence.
Abortifacient and galactogogic actions
Trachyspermum ammi is listed in 14 indigenous medicinal plants that were reported to have been used for abortion in some districts of Uttar Pradesh (India) in their survey conducted in 1987. Specifically, in the village of Kallipuschium, Lucknow district, 50 of the 75 pregnant women who were surveyed (of a total of 155 women in the fertile period) claimed to have used T. ammi seed for abortion. The herb was not 100% effective and so the possibility of causing congenital defects was of concern. There was a high risk of potential human fetotoxicity of ten plants including T. ammi, based on teratogenicity observed in rat foetuses.
The National Dairy Research Institute in India investigated the estrogenic content of some herbs (including T. ammi) that are traditionally used to increase milk yield in dairy cattle. T. ammi has also been traditionally used as a galactogogue in humans. The total phytoestrogen content of dry T. ammi seed was 473 ppm, which was the second highest in the list of eight herbs tested (total phytoestrogen contents 131-593 ppm).
Antiplatelet-aggregatory
Antiplatelet-Aggregatory experiments in vitro with blood from human volunteers, it showed that a dried ethereal extract of T. ammi seeds, inhibited aggregation of platelets induced by arachidonic acid, collagen and epinephrine. Research study was intended to support the traditional use of T. ammi in women post parturition.
Anti-inflammatory potential
Anti-inflammatory potential of the total alcoholic extract (TAE) and total aqueous extract (TAQ) of the Ajwain seeds was determined. TAE and TAQ exhibited significant (P<0.001) antiinflammatory activity in both the animal models. The weights of the adrenal glands were found to be significantly increased in TAE and TAQ treated animals. TAE and TAQ extracts from the ajwain seeds exhibit significant anti-inflammatory potential.
Antitussive effects
The antitussive effects of aerosols of two different concentrations of aqueous and macerated extracts and carvacrol, codeine, and saline were tested by counting the number of coughs produced. The results showed significant reduction of cough number obtained in the presence of both concentrations of aqueous and macerated extracts and codeine (P < 0.001 for extracts and P < 0.01 for codeine).
Antifilarial activity
In vitro activity of the methanolic extract of the fruits of Trachyspermum ammi (Apiaceae) against Setaria digitata worms has been investigated. The crude extract and the active fraction showed significant activity against the adult S. digitata by both a worm motility and MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide] reduction assays. The isolated active principle phenolic monoterpene screened for in vivo antifilarial activity against the human filarial worm B. malayi in Mastomys coucha showed macrofilaricidal activity and female worm sterility in vivo against B. malayi. T. ammi crude extract exhibited macrofilaricidal activity. The IC50 values for the isolated active principle 2- isopropyl-5-methyl phenol at two incubation periods 24 and 48 h were 0.024 and 0.002 mg/ml, respectively. The in vivo effect of the active principle 2-isopropyl-5-methyl phenol was evaluated against the B. malayi parasite in a Mastomys coucha model. The mean percentage mortality of adults (58.93%) in the group treated with 50 mg/kg was significantly (P<0.0001) higher than that was obtained in the control group (19.05%).
Gastro protective activity Trachyspermum ammi fruit showed antiulcer activity by using different ulcer models. Animals pre-treated with ethanolic extract showed significant decrease in ulcer index and percentage ulcer protection in all models. The results suggest that the extract showed significant protection (p<0.001) by reducing ulcerative lesions when compared with control group of animals.
Detoxification of aflatoxins
The seed extract of ajwain showed the maximum degradation of aflatoxin G1 (AFG1). The aflatoxin detoxifying activity of the seeds extract was significantly reduced upon boiling. Significant levels of degradation of other aflatoxins viz., AFB1, AFB2 and AFG2 by the dialyzed seeds extract were also observed. Time course study of AFG1 detoxification by dialyzed T. ammi extract showed that more than 91% degradation occurred at 24 h and 78% degradation occurred within 6 h after incubation.
Ameliorative effect
Effects of ajwain extract on hexachlorocyclohexane(HCH)-induced oxidative stress and toxicity in rats were investigated. Pre-feeding of ajwain extract resulted in increased GSH, GSH-peroxidase, G-6-PDH, SOD, catalase, glutathione S-transferase (GST) activities and decreased hepatic levels of lipid peroxides. It was concluded that HCH administration resulted in hepatic free radical stress, causing toxicity, which could be reduced by the dietary ajwain extract.

Antimicrobial actions in vitro
The antimicrobial actions of T. ammi, in the protection of foodstuffs against microbial spoilage, conducting laboratory assays of antimicrobial efficacy in vitro, and its use as antimicrobials in humans, are also investigated. The active principles thought to be responsible for the antimicrobial activity of ajwain were reported to be carvacol and thymol.  ‘Thymol kills the bacteria resistant to even prevalent third generation antibiotics and multi-drug resistant microbial pathogens and thus works as a plant based 4th generation herbal antibiotic formulation.Antifungal action of volatile constituents of T. ammi seeds on ten fungi (Acrophialophora fusispora, Curvularia lunata, Fusarium chlamydosporum, F. poae, Myrothecium roridum, Papulaspora sp., Alternaria grisea, A. tenuissima, Drechslera tetramera,., and Rhizoctonia solani) was tested and found to inhibit the growth of all test fungi by 72-90%. Phenolic compounds, such as thymol and carvacol, are known to be either bactericidal or bacteriostatic agents depending on the concentration used.
Hypolipidemic action in vivo
Antihyperlipidemic effect of T. ammi seed has been obtained in albino rabbits. It was assessed that T. ammi powder at a dose rate of 2 g/kg body weight and its equivalent methanol extract were extensively effective in lipid lowering action by decreased total cholesterol, LDL-cholesterol, triglycerides and total lipids.
Digestive stimulant actions in vivo and in vitro
T. ammi would increase the secretion of gastric acid; the addition of T. ammi to the infusion increased the amount of gastric acid. Gastric acid secretion was increased nearly four-fold by T. ammi. In experimental rats in vivo, the addition of T. ammi to the diet reduced food transit time and also enhanced the activity of digestive enzymes and/or caused a higher secretion of bile acids.
Nematicidal activity
Pine Wilt disease is caused by the pinewood nematode (PWN), Bursaphelenchus xylophilus. Nematicidal activity of ajwain oil constituents (camphene, pinene, myrcene, limonene, terpinene, terpinen- 4-ol, thymol and carvacrol) is against PWN. PWN bodies are treated with the muscle activity blockers levamisole hydrochloride and morantal tatrate. Amino and hydroxyl groups have been hypothesized as target sites of methyl isothiocyanate in nematodes. Some essential oils have been reported to interfere with the neuromodulator octopamine or GABA-gated chloride channels of insect pests. Thymol and carvacrol are very effective against PWN. These studies confirm that the nematicidal activity of ajwain oil is mainly attributed to the activity of thymol and carvacrol. Nematicidal activity of ajwain essential oils LC50 values was 0.431 mg/ml.
Anthelmintic activity Anthelmintic activity of T. ammi shows its effect against specific helminths, e.g. Ascaris lumbricoides in humans and Haemonchus contortus in sheep. Anthelmintic activity of T. ammi exerts by interference with the energy metabolism of parasites through potentiation of ATPase activity and thus loss of energy reserves. The plant has also been reported to possess cholinergic activity with peristaltic movements of the gut, thus helping in expulsion of intestinal parasites which might also be a contributory factor to its anthelmintic activity.
AFP: One of the ref. - Ajwain water use to prepare Anjan
Ayulink Ayurveda: ajwain + sharkara (rock sugar) is good for prevention of sunstroke
AFP: Can we use Ajwain taila in Toothache? Ajmo steam - Cold
Ayulink Ayurveda: any recipe for general consumption from ajwain? n Gujarat, we use Raab - a recipe with wheat flour + ghee+ jaggery or sugar + ajwain for general strength and prevent cold and cough. ajwain tea for indigestion, bloating and anorexia.
AFP: In Gujarat traditionally we prepare Vegetable Gavar with Ajwain to make it easily digestible
Ayulink Ayurveda: In kids, for prevention of respiratory diseases, usually roasted ajwain seeds are packed in a small cotton bag (like tavij) and kept on chest area.
Vd. Dhruti Kagrana: Ajmodadi churna
Ayulink Ayurveda: It is good for aamavata condition. some times vaidyas use ajwain oil for joint pain too
Vd. Dhruti Kagrana: Charaka samhita - Ajmo in Shulaprashamana
Ayulink Ayurveda: ajwain + hing + haritaki + sindhav = good for colitis or IBS
Vd. Dhruti Kagrana: its excess can destroy sperms (Bhavprakash Nighantu)
Ayulink Ayurveda: fried pakora from fresh ajwain leaves are very known in monsson season in Gujarat
Ayucafe 012019 06: Boil milk with tap ajwain to give kids for kaphprakruti and also in cough
Dr. Yashswi Mehta: Ajmo seeds in lukewarm  mustard oil...and given massage infant babies with it in treble areas..
Ayulink Ayurveda: when used in cooking , it helps to control remove smell of hing (asafetida). two drops of ajwain oil can be used to ease a dreaded ear pain. For instant relief from tooth-ache, gargle with a mix of lukewarm water, 1 teaspoon of ajwain and salt.
AFP: Ajwain leaves - Shulkruta ( ref. Bhavprakash) Shulakrut : May produce pain
Ayucafe 012019 06: Paratha are heavy to digest so add ajwain in making dough and also some black paper too
Ayulink Ayurveda: But what about fried pakora? We love to eat and it is always good for cold and cough
AFP: Different name of Ajwain
- Yanika
- Ugragandha
- Brahmadarbha
- Ajmodika
- Dipyaka
- Dipya
Ayulink Ayurveda: thymol in ajwain seeds acts as a strong fungicide and germicide.
Thus, ajwain seeds can be crushed and applied on the skin to treat infections or cuts
89967: Can it apply on fungal infections??
Ayulink Ayurveda: *How to prepare ajwain water*
boil 2 teaspoons of roasted ajwain seeds in water.
Strain this mixture and drink.
Drinking ajwain water regularly is known to enhance your rate of metabolism, burns fat and thus helps in losing weight.
89967: Method to prepare it
Ayulink Ayurveda: yes, most of skin conditions, where kapha anubandha is there, ajwain can be useful
Manoj Advaith: Kanji and Ajwain with saidhava lavana is best in agnimandya
Ayulink Ayurveda: ajwain seeds + mustard oil - warm it and apply on a card board = can be used as mosquito repellant. yes..dierct application or mix with sesame oil. Some foreign doctors say that ajwain may lower the blood pressure. extract of ajwain used in petic ulcers in foreign contries. It is known as carom seeds out side India, But I am not sure exactly english name of ajwa
Vd. Akshata Swami: Ajamoda : its has good srotoshodhaka if taken as Our hydration drink regularly and instant relief of stomach cramps.
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Compiled by - Dr. Dhruti Kagrana


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