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Ayucafe – Live chat Topic of
Discussion: Uses
of Ajawain (Trachyspermum ammi) According to Ayurveda
Ayulink Ayurveda: it is laghu, ruksha, tikshna, kapha-vata
pacifying and pitta increasing
37811: Vat kaphnashak, Agnideepak , Pachak
Ayulink Ayurveda: vipaka katu and ushna virya
Prasad N Dhule: पेट के दर्द... मंदग्नी में use करते है
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for any kind of
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Dr. Bhavin Chavda: Kapha shamak or khansi me useful
37811: Kruminashak
Dr. Jigar Joshi: Aamvat me useful
37811: Vedanashamak. In cold and headache hot ajwain
fomentation gives superb relief
Dr. Bhavin Chavda: Ama hara Shola hara
Dr. Arvind Shahane: In udaradhman Ajwain + black salt
Very useful home remedy
Ayulink Ayurveda: It is useful in almost all
respiratory disorders
AFP: Ajmo + Jaggery - Urticaria
Dr. Archana Panchal: In urticaria ajwain haldi very
useful
Ayulink Ayurveda: friends pl share recipe also -
how to use in particular conditions for example, ajwain churna to eat in mandagni.
ajwain for steam inhalation in cold. With cotton bag like pind sveda?
Dr. Arvind Shahane: Please specify hot Ajwain
formation
37811: Yes
Ayulink Ayurveda: i use it - pind sveda (cotton
bag) in aamavata condition
37811: Just roast 1tsp ajwain on iorn pot inhale smoke then
keep it in small handkerchief and slowly smell it
Ayulink Ayurveda: Very good to use in kids
89967: In excess amount -- can it cause burning micturition
and piles problem ???
Vd. Dhruti Kagrana: Ruchikara
37811: Yes. Shek- Dry swed
Ayulink Ayurveda: It is diuretic too. But in excess
it can cause side effects with ushba virya
37811: After delivery used for dhupan with other
ingredients for baby and mother
Ayulink Ayurveda: Very strong smell due to volatile
oil in it
Dr. Nahida Tarannum: It is vata anulomak..gives best
results in indigestion too..
AFP: Ajmo - Good in spasmodic pain
Ayulink Ayurveda: Sometimes smell / local
application of volatile oil can cause skin irritations
37811: Yes so when we used in wheat flour paratha to make
it easily digestive
Ayulink Ayurveda: It is described as krumighna in
the books. Good - it increases Ruchi in the food
06050: Ajmo salt & hingu give relief in gastric pain
37811: Yes always first tried in stomach aches
Dr. Yashswi Mehta: What's ratio ajmo+ jaggery...?
Ayulink Ayurveda: It is also mentioned in the book
as hruday uttejak
AFP: Ajmo 1part Jaggery 3part
37811: I used in mukhavas with variali ( badishep) and Til(
sesame) kala namak
AFP: Ajmo is also given good result in PMS & Kashtaartava
Dr. Arvind Shahane: As a daily mukhwas or like
vatshamak mukhwas?
Ayulink Ayurveda: Is there any ready made formula
with Ajwain as main ingredient ?
37811: Daily
AFP: Ajmodadi vati
Ayulink Ayurveda: Ajmidadi churna? Vati?
AFP: Ajmodadi vati - Ref
: Aryabhishaka
Ayulink Ayurveda: It is also good to control hikka
I think it is used in
dhoompan - Nirdosh herbal cig
88776: Ajvain : katu, tikt, laghu, ruksh, ushna, dipak,
grahi, vatnashak, kafanashak, pittakarak. shul nashak , krimi nashak , hikka
aamvata, aanah, aruchi nashak.
AFP: Frequent Urination : Ajmo + Til(Sesame)
Ayucafe 032019 23: Ajwain with its characteristic
aromatic smell and pungent taste is widely used as a spice in curries. Its
seeds are used in small quantities for flavoring numerous foods, as
preservatives, in medicine and for the manufacture of essential oil in
perfumery. In Indian system of medicine, ajwain is administered for curing
stomach disorders, a paste of crushed fruits is applied externally for
relieving colic pains; and a hot and dry fomentation of the fruits is applied
on chest for asthma. T. ammi has been shown to possess antimicrobial, hypolipidemic, digestive stimulant,
antihypertensive, hepatoprotective, antispasmodic, broncho-dilating, antilithiasis, diuretic, abortifacient , antiinflammatory, antitussive,
antifilarial, gestroprotective,
nematicidal, anthelmintic, detoxification of aflatoxins and ameliorative
effects.Therapeutic uses of T. ammi fruits include; stomachic, carminative and
expectorant, antiseptic and amoebiasis, antimicrobial. Seeds soaked in lemon
juice with Prunus amygdalus (badam) are given in curing amenhorroea and it is
also used as antipyretic, febrifugal and in the treatment of typhoid fever.
Antihypertensive, antispasmodic and broncho-dilating activity
The antihypertensive effect of T. ammi administered
intravenously in vivo, and the antispasmodic and broncho-dilating actions in
vitro showed that calcium channel blockade has been found to mediate the
spasmolytic effects of plant materials and it is being considered that this
mechanism contributed to their observed result and supported the traditional
use of T. ammi in hyperactive disease states of the gut such as colic and
diarrhea as well as in hypertension.
Hepatoprotective activity The hepatoprotective actions in
vivo showed that T. ammi was 80% protective in mice against a normally-lethal
dose of paracetamol (1 g/kg), it prevented the CCl4-induced prolongation of
pentobarbital sleeping time in mice, and it tended to normalize the high serum
levels of liver enzymes caused by CCl4-induced liver damage in rats.
Antilithiasis and diuretic activity
Antilithiasis and diuretic actions in vivo of T. ammi on
inhibiting oxalate urolithiasis induced in rats are also studied. In a further
study of a possible diuretic effect, it was found that T. ammi was not
effective in increasing the 24-h urine production. The results concluded that
the traditional use of T. ammi in the treatment of kidney stones was not
supported by their experimental evidence.
Abortifacient and galactogogic actions
Trachyspermum ammi is listed in 14 indigenous medicinal
plants that were reported to have been used for abortion in some districts of
Uttar Pradesh (India) in their survey conducted in 1987. Specifically, in the
village of Kallipuschium, Lucknow district, 50 of the 75 pregnant women who
were surveyed (of a total of 155 women in the fertile period) claimed to have
used T. ammi seed for abortion. The herb was not 100% effective and so the
possibility of causing congenital defects was of concern. There was a high risk
of potential human fetotoxicity of ten plants including T. ammi, based on
teratogenicity observed in rat foetuses.
The National Dairy Research Institute in India investigated
the estrogenic content of some herbs (including T. ammi) that are traditionally
used to increase milk yield in dairy cattle. T. ammi has also been
traditionally used as a galactogogue in humans. The total phytoestrogen content
of dry T. ammi seed was 473 ppm, which was the second highest in the list of
eight herbs tested (total phytoestrogen contents 131-593 ppm).
Antiplatelet-aggregatory
Antiplatelet-Aggregatory experiments in vitro with blood from
human volunteers, it showed that a dried ethereal extract of T. ammi seeds,
inhibited aggregation of platelets induced by arachidonic acid, collagen and
epinephrine. Research study was intended to support the traditional use of T.
ammi in women post parturition.
Anti-inflammatory potential
Anti-inflammatory potential of the total alcoholic extract
(TAE) and total aqueous extract (TAQ) of the Ajwain seeds was determined. TAE
and TAQ exhibited significant (P<0.001) antiinflammatory activity in both
the animal models. The weights of the adrenal glands were found to be
significantly increased in TAE and TAQ treated animals. TAE and TAQ extracts
from the ajwain seeds exhibit significant anti-inflammatory potential.
Antitussive effects
The antitussive effects of aerosols of two different
concentrations of aqueous and macerated extracts and carvacrol, codeine, and
saline were tested by counting the number of coughs produced. The results
showed significant reduction of cough number obtained in the presence of both
concentrations of aqueous and macerated extracts and codeine (P < 0.001 for
extracts and P < 0.01 for codeine).
Antifilarial activity
In vitro activity of the methanolic extract of the fruits of
Trachyspermum ammi (Apiaceae) against Setaria digitata worms has been
investigated. The crude extract and the active fraction showed significant
activity against the adult S. digitata by both a worm motility and MTT [3-(4,
5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide] reduction assays.
The isolated active principle phenolic monoterpene screened for in vivo
antifilarial activity against the human filarial worm B. malayi in Mastomys
coucha showed macrofilaricidal activity and female worm sterility in vivo
against B. malayi. T. ammi crude extract exhibited macrofilaricidal activity.
The IC50 values for the isolated active principle 2- isopropyl-5-methyl phenol
at two incubation periods 24 and 48 h were 0.024 and 0.002 mg/ml, respectively.
The in vivo effect of the active principle 2-isopropyl-5-methyl phenol was
evaluated against the B. malayi parasite in a Mastomys coucha model. The mean
percentage mortality of adults (58.93%) in the group treated with 50 mg/kg was
significantly (P<0.0001) higher than that was obtained in the control group
(19.05%).
Gastro protective activity Trachyspermum ammi fruit showed
antiulcer activity by using different ulcer models. Animals pre-treated with
ethanolic extract showed significant decrease in ulcer index and percentage
ulcer protection in all models. The results suggest that the extract showed
significant protection (p<0.001) by reducing ulcerative lesions when
compared with control group of animals.
Detoxification of aflatoxins
The seed extract of ajwain showed the maximum degradation of
aflatoxin G1 (AFG1). The aflatoxin detoxifying activity of the seeds extract
was significantly reduced upon boiling. Significant levels of degradation of
other aflatoxins viz., AFB1, AFB2 and AFG2 by the dialyzed seeds extract were
also observed. Time course study of AFG1 detoxification by dialyzed T. ammi
extract showed that more than 91% degradation occurred at 24 h and 78%
degradation occurred within 6 h after incubation.
Ameliorative effect
Effects of ajwain extract on hexachlorocyclohexane(HCH)-induced
oxidative stress and toxicity in rats were investigated. Pre-feeding of ajwain
extract resulted in increased GSH, GSH-peroxidase, G-6-PDH, SOD, catalase,
glutathione S-transferase (GST) activities and decreased hepatic levels of lipid
peroxides. It was concluded that HCH administration resulted in hepatic free
radical stress, causing toxicity, which could be reduced by the dietary ajwain
extract.
Antimicrobial actions in vitro
The antimicrobial actions of T. ammi, in the protection of
foodstuffs against microbial spoilage, conducting laboratory assays of
antimicrobial efficacy in vitro, and its use as antimicrobials in humans, are
also investigated. The active principles thought to be responsible for the
antimicrobial activity of ajwain were reported to be carvacol and thymol. ‘Thymol kills the bacteria resistant to even
prevalent third generation antibiotics and multi-drug resistant microbial
pathogens and thus works as a plant based 4th generation herbal antibiotic
formulation.Antifungal action of volatile constituents of T. ammi seeds on ten
fungi (Acrophialophora fusispora, Curvularia lunata, Fusarium chlamydosporum,
F. poae, Myrothecium roridum, Papulaspora sp., Alternaria grisea, A.
tenuissima, Drechslera tetramera,., and Rhizoctonia solani) was tested and
found to inhibit the growth of all test fungi by 72-90%. Phenolic compounds,
such as thymol and carvacol, are known to be either bactericidal or
bacteriostatic agents depending on the concentration used.
Hypolipidemic action in vivo
Antihyperlipidemic effect of T. ammi seed has been obtained
in albino rabbits. It was assessed that T. ammi powder at a dose rate of 2 g/kg
body weight and its equivalent methanol extract were extensively effective in
lipid lowering action by decreased total cholesterol, LDL-cholesterol,
triglycerides and total lipids.
Digestive stimulant actions in vivo and in vitro
T. ammi would increase the secretion of gastric acid; the
addition of T. ammi to the infusion increased the amount of gastric acid.
Gastric acid secretion was increased nearly four-fold by T. ammi. In
experimental rats in vivo, the addition of T. ammi to the diet reduced food
transit time and also enhanced the activity of digestive enzymes and/or caused
a higher secretion of bile acids.
Nematicidal activity
Pine Wilt disease is caused by the pinewood nematode (PWN),
Bursaphelenchus xylophilus. Nematicidal activity of ajwain oil constituents
(camphene, pinene, myrcene, limonene, terpinene, terpinen- 4-ol, thymol and
carvacrol) is against PWN. PWN bodies are treated with the muscle activity
blockers levamisole hydrochloride and morantal tatrate. Amino and hydroxyl
groups have been hypothesized as target sites of methyl isothiocyanate in
nematodes. Some essential oils have been reported to interfere with the
neuromodulator octopamine or GABA-gated chloride channels of insect pests.
Thymol and carvacrol are very effective against PWN. These studies confirm that
the nematicidal activity of ajwain oil is mainly attributed to the activity of
thymol and carvacrol. Nematicidal activity of ajwain essential oils LC50 values
was 0.431 mg/ml.
Anthelmintic activity Anthelmintic activity of T. ammi shows
its effect against specific helminths, e.g. Ascaris lumbricoides in humans and
Haemonchus contortus in sheep. Anthelmintic activity of T. ammi exerts by
interference with the energy metabolism of parasites through potentiation of
ATPase activity and thus loss of energy reserves. The plant has also been
reported to possess cholinergic activity with peristaltic movements of the gut,
thus helping in expulsion of intestinal parasites which might also be a
contributory factor to its anthelmintic activity.
AFP: One of the ref. - Ajwain water use to prepare Anjan
Ayulink Ayurveda: ajwain + sharkara (rock sugar) is
good for prevention of sunstroke
AFP: Can we use Ajwain taila in Toothache? Ajmo steam -
Cold
Ayulink Ayurveda: any recipe for general
consumption from ajwain? n Gujarat, we use Raab - a recipe with wheat flour +
ghee+ jaggery or sugar + ajwain for general strength and prevent cold and cough.
ajwain tea for indigestion, bloating and anorexia.
AFP: In Gujarat traditionally we prepare Vegetable Gavar
with Ajwain to make it easily digestible
Ayulink Ayurveda: In kids, for prevention of
respiratory diseases, usually roasted ajwain seeds are packed in a small cotton
bag (like tavij) and kept on chest area.
Vd. Dhruti Kagrana: Ajmodadi churna
Ayulink Ayurveda: It is good for aamavata condition.
some times vaidyas use ajwain oil for joint pain too
Vd. Dhruti Kagrana: Charaka samhita - Ajmo in
Shulaprashamana
Ayulink Ayurveda: ajwain + hing + haritaki +
sindhav = good for colitis or IBS
Vd. Dhruti Kagrana: its excess can destroy sperms
(Bhavprakash Nighantu)
Ayulink Ayurveda: fried pakora from fresh ajwain
leaves are very known in monsson season in Gujarat
Ayucafe 012019 06: Boil milk with tap ajwain to give
kids for kaphprakruti and also in cough
Dr. Yashswi Mehta: Ajmo seeds in lukewarm mustard oil...and given massage infant babies
with it in treble areas..
Ayulink Ayurveda: when used in cooking , it helps
to control remove smell of hing (asafetida). two drops of ajwain oil can be
used to ease a dreaded ear pain. For instant relief from tooth-ache, gargle
with a mix of lukewarm water, 1 teaspoon of ajwain and salt.
AFP: Ajwain leaves - Shulkruta ( ref. Bhavprakash) Shulakrut
: May produce pain
Ayucafe 012019 06: Paratha are heavy to digest so
add ajwain in making dough and also some black paper too
Ayulink Ayurveda: But what about fried pakora? We
love to eat and it is always good for cold and cough
AFP: Different name of Ajwain
- Yanika
- Ugragandha
- Brahmadarbha
- Ajmodika
- Dipyaka
- Dipya
Ayulink Ayurveda: thymol in ajwain seeds acts as a
strong fungicide and germicide.
Thus, ajwain seeds can be crushed and applied on the skin to
treat infections or cuts
89967: Can it apply on fungal infections??
Ayulink Ayurveda: *How to prepare ajwain water*
boil 2 teaspoons of roasted ajwain seeds in water.
Strain this mixture and drink.
Drinking ajwain water regularly is known to enhance your rate
of metabolism, burns fat and thus helps in losing weight.
89967: Method to prepare it
Ayulink Ayurveda: yes, most of skin conditions,
where kapha anubandha is there, ajwain can be useful
Manoj Advaith: Kanji and Ajwain with saidhava
lavana is best in agnimandya
Ayulink Ayurveda: ajwain seeds + mustard oil - warm
it and apply on a card board = can be used as mosquito repellant. yes..dierct
application or mix with sesame oil. Some foreign doctors say that ajwain may
lower the blood pressure. extract of ajwain used in petic ulcers in foreign
contries. It is known as carom seeds out side India, But I am not sure exactly
english name of ajwa
Vd. Akshata Swami: Ajamoda : its has good
srotoshodhaka if taken as Our hydration drink regularly and instant relief of
stomach cramps.
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Compiled by - Dr. Dhruti Kagrana
